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PDK1 plays a vital role on hematopoietic stem cell function

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a pivotal regulator in the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway that have been shown to play key roles in the functional development of B and T cells via activation of AGC protein kinases during hematopoiesis. However, the rol...

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Detalles Bibliográficos
Autores principales: Hu, Tianyuan, Li, Cong, Wang, Le, Zhang, Yingchi, Peng, Luyun, Cheng, Hui, Chu, Yajing, Wang, Weili, Ema, Hideo, Gao, Yingdai, Ju, Zhenyu, Yang, Zhongzhou, Wang, Xiaomin, Cheng, Tao, Yuan, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504031/
https://www.ncbi.nlm.nih.gov/pubmed/28694518
http://dx.doi.org/10.1038/s41598-017-05213-3