RNA Misprocessing in C9orf72-Linked Neurodegeneration

A large GGGGCC hexanucleotide repeat expansion in the first intron or promoter region of the C9orf72 gene is the most common genetic cause of familial and sporadic Amyotrophic lateral sclerosis (ALS), a devastating degenerative disease of motor neurons, and of Frontotemporal Dementia (FTD), the seco...

Descripción completa

Detalles Bibliográficos
Autores principales: Barker, Holly V., Niblock, Michael, Lee, Youn-Bok, Shaw, Christopher E., Gallo, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504096/
https://www.ncbi.nlm.nih.gov/pubmed/28744202
http://dx.doi.org/10.3389/fncel.2017.00195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504096/
https://www.ncbi.nlm.nih.gov/pubmed/28744202
http://dx.doi.org/10.3389/fncel.2017.00195

Ejemplares similares