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RNA Misprocessing in C9orf72-Linked Neurodegeneration

A large GGGGCC hexanucleotide repeat expansion in the first intron or promoter region of the C9orf72 gene is the most common genetic cause of familial and sporadic Amyotrophic lateral sclerosis (ALS), a devastating degenerative disease of motor neurons, and of Frontotemporal Dementia (FTD), the seco...

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Detalles Bibliográficos
Autores principales:	Barker, Holly V., Niblock, Michael, Lee, Youn-Bok, Shaw, Christopher E., Gallo, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504096/ https://www.ncbi.nlm.nih.gov/pubmed/28744202 http://dx.doi.org/10.3389/fncel.2017.00195

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