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Staphylococcus aureus Quorum Regulator SarA Targeted Compound, 2-[(Methylamino)methyl]phenol Inhibits Biofilm and Down-Regulates Virulence Genes

Staphylococcus aureus is a widely acknowledged Gram-positive pathogen for forming biofilm and virulence gene expressions by quorum sensing (QS), a cell to cell communication process. The quorum regulator SarA of S. aureus up-regulates the expression of many virulence factors including biofilm format...

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Detalles Bibliográficos
Autores principales: Balamurugan, P., Praveen Krishna, V., Bharath, D., Lavanya, Raajaraam, Vairaprakash, Pothiappan, Adline Princy, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504099/
https://www.ncbi.nlm.nih.gov/pubmed/28744275
http://dx.doi.org/10.3389/fmicb.2017.01290