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Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation

The frequent re-isolation of known compounds is one of the major challenges in drug discovery. Many biosynthetic genes are not expressed under standard culture conditions, thus limiting the chemical diversity of microbial compounds that can be obtained through fermentation. On the other hand, the co...

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Detalles Bibliográficos
Autores principales: Wakefield, Jennifer, Hassan, Hossam M., Jaspars, Marcel, Ebel, Rainer, Rateb, Mostafa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504103/
https://www.ncbi.nlm.nih.gov/pubmed/28744271
http://dx.doi.org/10.3389/fmicb.2017.01284