Neuronal Cholesterol Accumulation Induced by Cyp46a1 Down-Regulation in Mouse Hippocampus Disrupts Brain Lipid Homeostasis

Impairment in cholesterol metabolism is associated with many neurodegenerative disorders including Alzheimer's disease (AD). However, the lipid alterations underlying neurodegeneration and the connection between altered cholesterol levels and AD remains not fully understood. We recently showed...

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Detalles Bibliográficos
Autores principales: Ayciriex, Sophie, Djelti, Fathia, Alves, Sandro, Regazzetti, Anne, Gaudin, Mathieu, Varin, Jennifer, Langui, Dominique, Bièche, Ivan, Hudry, Eloise, Dargère, Delphine, Aubourg, Patrick, Auzeil, Nicolas, Laprévote, Olivier, Cartier, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504187/
https://www.ncbi.nlm.nih.gov/pubmed/28744197
http://dx.doi.org/10.3389/fnmol.2017.00211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504187/
https://www.ncbi.nlm.nih.gov/pubmed/28744197
http://dx.doi.org/10.3389/fnmol.2017.00211

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