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Downregulated Translation Initiation Signaling Predisposes Low-Birth-Weight Neonatal Pigs to Slower Rates of Muscle Protein Synthesis

Low-birth-weight (LBWT) neonates experience restricted muscle growth in their perinatal life. Our aim was to investigate the mechanisms that contribute to slower skeletal muscle growth of LBWT neonatal pigs. Twenty-four 1-day old male LBWT (816 ± 55 g) and normal-birth-weight (NBWT; 1,642 ± 55 g) li...

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Detalles Bibliográficos
Autores principales: Chen, Ying, McCauley, Sydney R., Johnson, Sally E., Rhoads, Robert P., El-Kadi, Samer W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504233/
https://www.ncbi.nlm.nih.gov/pubmed/28744224
http://dx.doi.org/10.3389/fphys.2017.00482