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Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation

TLR4 in intestinal epithelial cells has been shown both inflammatory and homeostatic roles following binding of its cognate ligand lipopolysaccharide (LPS). TWEAK-Fn14 axis plays an important role in pathologies caused by excessive or abnormal inflammatory responses. This study aimed to evaluate pot...

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Detalles Bibliográficos
Autores principales: Qi, Xuefeng, Qin, Lijuan, Du, Ruijing, Chen, Yungang, Lei, Mingzhu, Deng, Meiyu, Wang, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504244/
https://www.ncbi.nlm.nih.gov/pubmed/28744451
http://dx.doi.org/10.3389/fcimb.2017.00315