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Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation
TLR4 in intestinal epithelial cells has been shown both inflammatory and homeostatic roles following binding of its cognate ligand lipopolysaccharide (LPS). TWEAK-Fn14 axis plays an important role in pathologies caused by excessive or abnormal inflammatory responses. This study aimed to evaluate pot...
Autores principales: | Qi, Xuefeng, Qin, Lijuan, Du, Ruijing, Chen, Yungang, Lei, Mingzhu, Deng, Meiyu, Wang, Jingyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504244/ https://www.ncbi.nlm.nih.gov/pubmed/28744451 http://dx.doi.org/10.3389/fcimb.2017.00315 |
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