CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation

In germinal centres (GC) mature B cells undergo intense proliferation and immunoglobulin gene modification before they differentiate into memory B cells or long-lived plasma cells (PC). GC B-cell-to-PC transition involves a major transcriptional switch that promotes a halt in cell proliferation and...

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Detalles Bibliográficos
Autores principales: Pérez-García, Arantxa, Marina-Zárate, Ester, Álvarez-Prado, Ángel F., Ligos, Jose M., Galjart, Niels, Ramiro, Almudena R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504274/
https://www.ncbi.nlm.nih.gov/pubmed/28677680
http://dx.doi.org/10.1038/ncomms16067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504274/
https://www.ncbi.nlm.nih.gov/pubmed/28677680
http://dx.doi.org/10.1038/ncomms16067

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