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Utilization of Mechanistic Enzymology to Evaluate the Significance of ADP Binding to Human Lon Protease
Lon, also known as Protease La, is one of the simplest ATP-dependent proteases. It is a homooligomeric enzyme comprised of an ATPase domain and a proteolytic domain in each enzyme subunit. Despite sharing about 40% sequence identity, human and Escherichia coli Lon proteases utilize a highly conserve...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504276/ https://www.ncbi.nlm.nih.gov/pubmed/28744459 http://dx.doi.org/10.3389/fmolb.2017.00047 |