Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization

HER2 is a receptor tyrosine kinase, which is amplified and overexpressed in a subset of human cancers including breast and gastric cancers, and is indicated in its involvement in progression of cancer. Although its specific ligand(s) has not been detected, HER2 homodimerization, which is critical fo...

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Detalles Bibliográficos
Autores principales: Yoshioka, Yuichiro, Suzuki, Takehiro, Matsuo, Yo, Tsurita, Giichiro, Watanabe, Toshiaki, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504314/
https://www.ncbi.nlm.nih.gov/pubmed/28639750
http://dx.doi.org/10.1002/cam4.1099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504314/
https://www.ncbi.nlm.nih.gov/pubmed/28639750
http://dx.doi.org/10.1002/cam4.1099

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