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Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization
HER2 is a receptor tyrosine kinase, which is amplified and overexpressed in a subset of human cancers including breast and gastric cancers, and is indicated in its involvement in progression of cancer. Although its specific ligand(s) has not been detected, HER2 homodimerization, which is critical fo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504314/ https://www.ncbi.nlm.nih.gov/pubmed/28639750 http://dx.doi.org/10.1002/cam4.1099 |