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Exploring Site-Specific N-Glycosylation of HEK293 and Plant-Produced Human IgA Isotypes

[Image: see text] The full potential of recombinant Immunoglobulin A as therapeutic antibody is not fully explored, owing to the fact that structure–function relationships of these extensively glycosylated proteins are not well understood. Here monomeric IgA1, IgA2m(1), and IgA2m(2) variants of the...

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Detalles Bibliográficos
Autores principales: Göritzer, Kathrin, Maresch, Daniel, Altmann, Friedrich, Obinger, Christian, Strasser, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504489/
https://www.ncbi.nlm.nih.gov/pubmed/28516782
http://dx.doi.org/10.1021/acs.jproteome.7b00121