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Incorporating biological information in sparse principal component analysis with application to genomic data
BACKGROUND: Sparse principal component analysis (PCA) is a popular tool for dimensionality reduction, pattern recognition, and visualization of high dimensional data. It has been recognized that complex biological mechanisms occur through concerted relationships of multiple genes working in networks...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504598/ https://www.ncbi.nlm.nih.gov/pubmed/28697740 http://dx.doi.org/10.1186/s12859-017-1740-7 |