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Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

BACKGROUND: The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic plaque formation and rupture. Our previous study revealed the rhythmic expression...

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Detalles Bibliográficos
Autores principales: Lin, Changpo, Tang, Xiao, Xu, Lirong, Qian, Ruizhe, Shi, Zhenyu, Wang, Lixin, Cai, Tingting, Yan, Dong, Fu, Weiguo, Guo, Daqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504704/
https://www.ncbi.nlm.nih.gov/pubmed/28693506
http://dx.doi.org/10.1186/s12944-017-0500-z