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Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells
BACKGROUND: The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic plaque formation and rupture. Our previous study revealed the rhythmic expression...
Autores principales: | Lin, Changpo, Tang, Xiao, Xu, Lirong, Qian, Ruizhe, Shi, Zhenyu, Wang, Lixin, Cai, Tingting, Yan, Dong, Fu, Weiguo, Guo, Daqiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504704/ https://www.ncbi.nlm.nih.gov/pubmed/28693506 http://dx.doi.org/10.1186/s12944-017-0500-z |
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