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Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

BACKGROUND: The underlying biological mechanisms through which epidemiologically defined breast cancer risk factors contribute to disease risk remain poorly understood. Identification of the molecular changes associated with cancer risk factors in normal tissues may aid in determining the earliest e...

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Detalles Bibliográficos
Autores principales: Johnson, Kevin C., Houseman, E. Andres, King, Jessica E., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504720/
https://www.ncbi.nlm.nih.gov/pubmed/28693600
http://dx.doi.org/10.1186/s13058-017-0873-y