Cargando…

Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

BACKGROUND: The underlying biological mechanisms through which epidemiologically defined breast cancer risk factors contribute to disease risk remain poorly understood. Identification of the molecular changes associated with cancer risk factors in normal tissues may aid in determining the earliest e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Kevin C., Houseman, E. Andres, King, Jessica E., Christensen, Brock C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504720/ https://www.ncbi.nlm.nih.gov/pubmed/28693600 http://dx.doi.org/10.1186/s13058-017-0873-y

Ejemplares similares

Genome-wide characterization of cytosine-specific 5-hydroxymethylation in normal breast tissue
por: Wilkins, Owen M., et al.
Publicado: (2019)

5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients
por: Johnson, Kevin C., et al.
Publicado: (2016)

Integrative DNA Methylation and Gene Expression Analyses Identify DNA Packaging and Epigenetic Regulatory Genes Associated with Low Motility Sperm
por: Pacheco, Sara E., et al.
Publicado: (2011)

Normal Cell-Type Epigenetics and Breast Cancer Classification: A Case Study of Cell Mixture–Adjusted Analysis of DNA Methylation Data from Tumors
por: Houseman, Eugene Andrés, et al.
Publicado: (2014)

DNA methylation arrays as surrogate measures of cell mixture distribution
por: Houseman, Eugene Andres, et al.
Publicado: (2012)

Breast Cancer DNA Methylation Profiles Are Associated with Tumor Size and Alcohol and Folate Intake
por: Christensen, Brock C., et al.
Publicado: (2010)

Deconvolution of DNA methylation identifies differentially methylated gene regions on 1p36 across breast cancer subtypes
por: Titus, Alexander J., et al.
Publicado: (2017)

Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context
por: Christensen, Brock C., et al.
Publicado: (2009)

Application of Novel Breast Biospecimen Cell-Type Adjustment Identifies Shared DNA Methylation Alterations in Breast Tissue and Milk with Breast Cancer–Risk Factors
por: Muse, Meghan E., et al.
Publicado: (2023)

Erratum to: Langevin SM, Houseman EA, Christensen BC, Wiencke JK, Nelson HH, Karagas MR, et al. The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood. Epigenetics 2011; 6
por: Langevin, Scott M., et al.
Publicado: (2012)

In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta
por: Wilhelm-Benartzi, Charlotte S., et al.
Publicado: (2011)

Effect of Regulatory Element DNA Methylation on Tissue-Type Plasminogen Activator Gene Expression
por: Dunoyer-Geindre, Sylvie, et al.
Publicado: (2016)

Tissue Specific DNA Methylation in Normal Human Breast Epithelium and in Breast Cancer
por: Avraham, Ayelet, et al.
Publicado: (2014)

DNA methylation age in paired tumor and adjacent normal breast tissue in Chinese women with breast cancer
por: Koka, Hela, et al.
Publicado: (2023)

The Influence of cis-Regulatory Elements on DNA Methylation Fidelity
por: Teng, Mingxiang, et al.
Publicado: (2012)

Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
por: Zhang, Weiwei, et al.
Publicado: (2015)

DNA methylation in the adipose tissue and whole blood of Agent Orange-exposed Operation Ranch Hand veterans: a pilot study
por: Rytel, Matthew R., et al.
Publicado: (2021)

Normal gastric tissue Helicobacter pylori infection is associated with epigenetic age acceleration, increased mitotic tick rate, tissue cell composition, and Natural Killer cell methylation alterations
por: Vlasac, Irma M., et al.
Publicado: (2023)

Quantitative reconstruction of leukocyte subsets using DNA methylation
por: Accomando, William P, et al.
Publicado: (2014)

Age-related DNA methylation in paired normal and tumour breast tissue in Chinese breast cancer patients
por: Kiely, Maeve, et al.
Publicado: (2020)

Reference-free cell mixture adjustments in analysis of DNA methylation data
por: Houseman, Eugene Andres, et al.
Publicado: (2014)

DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
por: Johnson, Kevin C., et al.
Publicado: (2015)

Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective
por: Houseman, E Andres, et al.
Publicado: (2015)

DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
por: Teschendorff, Andrew E, et al.
Publicado: (2016)

Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions
por: Houseman, E Andres, et al.
Publicado: (2008)

Review of processing and analysis methods for DNA methylation array data
por: Wilhelm-Benartzi, C S, et al.
Publicado: (2013)

Differential DNA Methylation in Umbilical Cord Blood of Infants Exposed to Low Levels of Arsenic in Utero
por: Koestler, Devin C., et al.
Publicado: (2013)

Reference-free deconvolution of DNA methylation data and mediation by cell composition effects
por: Houseman, E. Andres, et al.
Publicado: (2016)

DNA Methylation and Breast Cancer Risk: An Epigenome-Wide Study of Normal Breast Tissue and Blood
por: Ennour-Idrissi, Kaoutar, et al.
Publicado: (2020)

DNA methylation age is elevated in breast tissue of healthy women
por: Sehl, Mary E., et al.
Publicado: (2017)

Hormone therapy use and breast tissue DNA methylation: analysis of epigenome wide data from the normal breast study
por: Harlid, Sophia, et al.
Publicado: (2019)

Placental DNA Methylation Related to Both Infant Toenail Mercury and Adverse Neurobehavioral Outcomes
por: Maccani, Jennifer Z.J., et al.
Publicado: (2015)

Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements
por: Liu, Ying, et al.
Publicado: (2012)

DNA Methylation and Regulatory Elements during Chicken Germline Stem Cell Differentiation
por: He, Yanghua, et al.
Publicado: (2018)

Prediagnostic breast milk DNA methylation alterations in women who develop breast cancer
por: Salas, Lucas A, et al.
Publicado: (2020)

Validation of a DNA methylation reference panel for the estimation of nucleated cells types in cord blood
por: Cardenas, Andres, et al.
Publicado: (2016)

Serum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange
por: Kelsey, Karl T., et al.
Publicado: (2019)

DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants
por: Gao, Yang, et al.
Publicado: (2018)

Identification of Methylated Genes Associated with Aggressive Bladder Cancer
por: Marsit, Carmen J., et al.
Publicado: (2010)

Characterization of age signatures of DNA methylation in normal and cancer tissues from multiple studies
por: Kim, Jihyun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_cf7bu8htfejc46lidh0mnj5diq