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JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression

BACKGROUND: Jumonji C domain 2A (JMJD2A), as a histone demethylases, plays a vital role in tumorigenesis and progression. But, its functions and underlying mechanisms of JMJD2A in nasopharyngeal carcinoma (NPC) metabolism are remained to be clarified. In this study, we investigated glycolysis regula...

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Detalles Bibliográficos
Autores principales: Su, Yi, Yu, Qiu-hong, Wang, Xiang-yun, Yu, Li-ping, Wang, Zong-feng, Cao, Ying-chun, Li, Jian-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504777/
https://www.ncbi.nlm.nih.gov/pubmed/28693517
http://dx.doi.org/10.1186/s12885-017-3473-4