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JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression
BACKGROUND: Jumonji C domain 2A (JMJD2A), as a histone demethylases, plays a vital role in tumorigenesis and progression. But, its functions and underlying mechanisms of JMJD2A in nasopharyngeal carcinoma (NPC) metabolism are remained to be clarified. In this study, we investigated glycolysis regula...
Autores principales: | Su, Yi, Yu, Qiu-hong, Wang, Xiang-yun, Yu, Li-ping, Wang, Zong-feng, Cao, Ying-chun, Li, Jian-dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504777/ https://www.ncbi.nlm.nih.gov/pubmed/28693517 http://dx.doi.org/10.1186/s12885-017-3473-4 |
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