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Estimating Phred scores of Illumina base calls by logistic regression and sparse modeling
BACKGROUND: Phred quality scores are essential for downstream DNA analysis such as SNP detection and DNA assembly. Thus a valid model to define them is indispensable for any base-calling software. Recently, we developed the base-caller 3Dec for Illumina sequencing platforms, which reduces base-calli...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504792/ https://www.ncbi.nlm.nih.gov/pubmed/28697757 http://dx.doi.org/10.1186/s12859-017-1743-4 |