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Estimating Phred scores of Illumina base calls by logistic regression and sparse modeling

BACKGROUND: Phred quality scores are essential for downstream DNA analysis such as SNP detection and DNA assembly. Thus a valid model to define them is indispensable for any base-calling software. Recently, we developed the base-caller 3Dec for Illumina sequencing platforms, which reduces base-calli...

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Detalles Bibliográficos
Autores principales:	Zhang, Sheng, Wang, Bo, Wan, Lin, Li, Lei M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504792/ https://www.ncbi.nlm.nih.gov/pubmed/28697757 http://dx.doi.org/10.1186/s12859-017-1743-4

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