Sirolimus alters lung pathology and viral load following influenza A virus infection

BACKGROUND: Inhibitors of mTOR, such as sirolimus, have been shown to induce thymus involution and inflammatory lung disease in mice. The latter effect supports the role of this serine/threonine kinase in ameliorating lung inflammation. Other studies have shown sirolimus reduces/delays lung disease...

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Detalles Bibliográficos
Autores principales: Alsuwaidi, Ahmed R., George, Junu A., Almarzooqi, Saeeda, Hartwig, Stacey M., Varga, Steven M., Souid, Abdul-Kader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504865/
https://www.ncbi.nlm.nih.gov/pubmed/28693498
http://dx.doi.org/10.1186/s12931-017-0618-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504865/
https://www.ncbi.nlm.nih.gov/pubmed/28693498
http://dx.doi.org/10.1186/s12931-017-0618-6

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