IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype

Mesenchymal stem cell- (MSC-) based therapy is a promising treatment for cartilage. However, repair tissue in general fails to regenerate an original hyaline-like tissue. In this study, we focused on increasing the expression levels for insulin-like growth factor-1 (IGF-1) to improve repair tissue q...

Descripción completa

Detalles Bibliográficos
Autores principales: Ikeda, Yasutoshi, Sakaue, Morito, Chijimatsu, Ryota, Hart, David A., Otsubo, Hidenori, Shimomura, Kazunori, Madry, Henning, Suzuki, Tomoyuki, Yoshikawa, Hideki, Yamashita, Toshihiko, Nakamura, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504993/
https://www.ncbi.nlm.nih.gov/pubmed/28740513
http://dx.doi.org/10.1155/2017/5804147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504993/
https://www.ncbi.nlm.nih.gov/pubmed/28740513
http://dx.doi.org/10.1155/2017/5804147

Ejemplares similares