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Meiotic defects and decreased expression of genes located around the chromosomal breakpoint in the testis of a patient with a novel 46,X,t(Y;1)(p11.3;p31) translocation

Balanced translocations are known to be associated with infertility, spontaneous abortions and birth defects in mammals. Spermatocyte spreading and immunostaining were applied to detect meiotic prophase I progression, homologous chromosome pairing, synapsis and recombination in an azoospermic recipr...

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Detalles Bibliográficos
Autores principales: Li, Guangyuan, Iqbal, Furhan, Wang, Liu, Xu, Zhipeng, Che, Xiaoyan, Yu, Wen, Shi, Liang, Guo, Tonghang, Zhou, Guixiang, Jiang, Xiaohua, Zhang, Huan, Zhang, Yuanwei, Yu, Dexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504999/
https://www.ncbi.nlm.nih.gov/pubmed/28627638
http://dx.doi.org/10.3892/ijmm.2017.3029