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Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells

Temozolomide (TMZ) is an alkylating chemotherapeutic agent widely used in anti-glioma treatment. However, acquired TMZ resistance represents a major clinical challenge that leads to tumor relapse or progress. This study investigated the genomic profiles including long non-coding RNA (lncRNA) and mRN...

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Detalles Bibliográficos
Autores principales: Zeng, Huijun, Xu, Ningbo, Liu, Yanting, Liu, Boyang, Yang, Zhao, Fu, Zhao, Lian, Changlin, Guo, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505000/
https://www.ncbi.nlm.nih.gov/pubmed/28714520
http://dx.doi.org/10.3892/ijo.2017.4033