Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells

The bone marrow (BM) niche is a microenvironment promoting survival, dormancy and therapeutic resistance in tumor cells. Central to this function are mesenchymal stromal cells (MSCs). Here, using neuroblastoma (NB) as a model, we demonstrate that NB cells release an extracellular vesicle (EVs) whose...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakata, Rie, Shimada, Hiroyuki, Fernandez, G. Esteban, Fanter, Rob, Fabbri, Muller, Malvar, Jemily, Zimmermann, Pascale, DeClerck, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505006/
https://www.ncbi.nlm.nih.gov/pubmed/28717423
http://dx.doi.org/10.1080/20013078.2017.1332941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505006/
https://www.ncbi.nlm.nih.gov/pubmed/28717423
http://dx.doi.org/10.1080/20013078.2017.1332941

Ejemplares similares