Cargando…

Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells

The bone marrow (BM) niche is a microenvironment promoting survival, dormancy and therapeutic resistance in tumor cells. Central to this function are mesenchymal stromal cells (MSCs). Here, using neuroblastoma (NB) as a model, we demonstrate that NB cells release an extracellular vesicle (EVs) whose...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakata, Rie, Shimada, Hiroyuki, Fernandez, G. Esteban, Fanter, Rob, Fabbri, Muller, Malvar, Jemily, Zimmermann, Pascale, DeClerck, Yves A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505006/ https://www.ncbi.nlm.nih.gov/pubmed/28717423 http://dx.doi.org/10.1080/20013078.2017.1332941

Ejemplares similares

Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC
por: Hadjidaniel, Michael D., et al.
Publicado: (2017)

Fibroblasts and macrophages cooperate to create a pro-tumorigenic and immune resistant environment via activation of TGF-β/IL-6 pathway in neuroblastoma
por: Louault, Kevin, et al.
Publicado: (2022)

ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts
por: Al-Ansari, Mysoon M., et al.
Publicado: (2018)

Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
por: Jakhar, Rekha, et al.
Publicado: (2019)

Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity
por: Placencio, Veronica R., et al.
Publicado: (2015)

The Tumor Microenvironment in Neuroblastoma: New Players, New Mechanisms of Interaction and New Perspectives
por: Blavier, Laurence, et al.
Publicado: (2020)

Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells
por: Colletti, Marta, et al.
Publicado: (2020)

Bone Marrow Microenvironment and Tumor Progression
por: Chantrain, Christophe F., et al.
Publicado: (2008)

The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche
por: Blavier, Laurence, et al.
Publicado: (2023)

Carcinoma-Associated Mesenchymal Stem/Stromal Cells: Architects of the Pro-tumorigenic Tumor Microenvironment
por: Frisbie, Len, et al.
Publicado: (2022)

Permanent Pro-Tumorigenic Shift in Adipose Tissue-Derived Mesenchymal Stromal Cells Induced by Breast Malignancy
por: Plava, Jana, et al.
Publicado: (2020)

Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects
por: Nwabo Kamdje, Armel H., et al.
Publicado: (2020)

Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells
por: YAN, XIAOMIN, et al.
Publicado: (2015)

FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma
por: Ackermann, Sandra, et al.
Publicado: (2014)

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma
por: Wong, Matthew, et al.
Publicado: (2019)

The Metastatic Bone Marrow Niche in Neuroblastoma: Altered Phenotype and Function of Mesenchymal Stromal Cells
por: Hochheuser, Caroline, et al.
Publicado: (2020)

Initiation of immunotherapy with activated natural killer cells and anti-GD2 antibody dinutuximab prior to resection of primary neuroblastoma prolongs survival in mice
por: Zobel, Michael John, et al.
Publicado: (2020)

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity
por: Yang, Chia-Lung, et al.
Publicado: (2020)

Preclinical Evaluation of the Tumorigenic and Immunomodulatory Properties of Human Bone Marrow Mesenchymal Stromal Cell Populations with Clonal Trisomy 5
por: Marodin, Maria Susana Joya, et al.
Publicado: (2022)

Cancer Stem Cell-Exosomes, Unexposed Player in Tumorigenicity
por: Al-Sowayan, Batla S., et al.
Publicado: (2020)

LGG-23. Cardiac function in children and young adults treated with MEK inhibitors: a single institution retrospecive cohort study
por: Robison, Nathan, et al.
Publicado: (2022)

COVID-19 in Children, Adolescents and Young Adults with Hematological Malignancies
por: Parker, Rebecca S, et al.
Publicado: (2021)

CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic
por: Marshall, A D, et al.
Publicado: (2017)

Pro-Tumorigenic and Thrombotic Activities of Platelets in Lung Cancer
por: Anderson, Ronald, et al.
Publicado: (2023)

Extracellular vesicles derived from renal cancer stem cells induce a pro-tumorigenic phenotype in mesenchymal stromal cells
por: Lindoso, Rafael Soares, et al.
Publicado: (2015)

Glucose Enhances Pro-Tumorigenic Functions of Mammary Adipose-Derived Mesenchymal Stromal/Stem Cells on Breast Cancer Cell Lines
por: Ambrosio, Maria Rosaria, et al.
Publicado: (2022)

Exosomes in Neuroblastoma Biology, Diagnosis, and Treatment
por: Jahangiri, Leila, et al.
Publicado: (2022)

The Role of Cancer-Derived Exosomes in Tumorigenicity & Epithelial-to-Mesenchymal Transition
por: Blackwell, Robert H., et al.
Publicado: (2017)

Pro-Inflammatory Cytokine Priming and Purification Method Modulate the Impact of Exosomes Derived from Equine Bone Marrow Mesenchymal Stromal Cells on Equine Articular Chondrocytes
por: Jammes, Manon, et al.
Publicado: (2023)

2437 A prospective study of cancer clinical trial availability and enrollment among adolescents/young adults treated at a Children’s Hospital or Affiliated Adult Cancer Specialty Hospital
por: Thomas, Stefanie M., et al.
Publicado: (2018)

LGG-62. Weight change in pediatric patients treated with MEK inhibitors: a retrospective cohort study
por: Hyun Bahng, Hye, et al.
Publicado: (2022)

Bone Marrow Environment in Metastatic Neuroblastoma
por: Brignole, Chiara, et al.
Publicado: (2021)

Suppression of Cell Tumorigenicity by Non-neural Pro-differentiation Factors via Inhibition of Neural Property in Tumorigenic Cells
por: Yang, Xiaoli, et al.
Publicado: (2021)

Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics
por: Ricci, Biancamaria, et al.
Publicado: (2020)

MicroRNAs define distinct human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicity
por: Samaraweera, Leleesha, et al.
Publicado: (2014)

Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity
por: Alptekin, Ahmet, et al.
Publicado: (2019)

Pro‐tumorigenic role of ERα in prostate cancer cells
por: Furic, Luc, et al.
Publicado: (2015)

Therapeutic yoga reduces pro-tumorigenic cytokines in cancer survivors
por: Patel, Darpan I., et al.
Publicado: (2022)

OTHR-09. A RETROSPECTIVE COHORT STUDY EXAMINING RADIOLOGIC AND CLINICAL CHARACTERISTICS OF CHILDREN AND ADOLESCENTS WITH ATYPICAL/COMPLEX PINEAL CYSTS
por: Tahbaz, Meghan, et al.
Publicado: (2023)

Transcriptional co-activator TAZ sustains proliferation and tumorigenicity of neuroblastoma by targeting CTGF and PDGF-β
por: Wang, Mei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_v5c15bittc71rfkkj1trg0e222