Silencing of LSD1 gene modulates histone methylation and acetylation and induces the apoptosis of JeKo-1 and MOLT-4 cells

Lysine-specific demethylase 1 (LSD1) has been identified and biochemically characterized in epigenetics; however, the pathological roles of its dysfunction in mantle cell lymphoma (MCL) and T-cell acute lymphoblastic leukemia remain to be elucidated. In this study, we evaluated LSD1, and histone H3...

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Detalles Bibliográficos
Autores principales: Zou, Zhong-Kai, Huang, Yi-Qun, Zou, Yong, Zheng, Xu-Ke, Ma, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505009/
https://www.ncbi.nlm.nih.gov/pubmed/28627608
http://dx.doi.org/10.3892/ijmm.2017.3032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505009/
https://www.ncbi.nlm.nih.gov/pubmed/28627608
http://dx.doi.org/10.3892/ijmm.2017.3032

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