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Silencing of LSD1 gene modulates histone methylation and acetylation and induces the apoptosis of JeKo-1 and MOLT-4 cells
Lysine-specific demethylase 1 (LSD1) has been identified and biochemically characterized in epigenetics; however, the pathological roles of its dysfunction in mantle cell lymphoma (MCL) and T-cell acute lymphoblastic leukemia remain to be elucidated. In this study, we evaluated LSD1, and histone H3...
Autores principales: | Zou, Zhong-Kai, Huang, Yi-Qun, Zou, Yong, Zheng, Xu-Ke, Ma, Xu-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505009/ https://www.ncbi.nlm.nih.gov/pubmed/28627608 http://dx.doi.org/10.3892/ijmm.2017.3032 |
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