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Triptolide exerts protective effects against fibrosis following ileocolonic anastomosis by mechanisms involving the miR-16-1/HSP70 pathway in IL-10-deficient mice

Surgeries, particularly ileocecal resection (ICR), are often required in the treatment of Crohn's disease (CD). However, recurrences are common for patients who undergo ICR, and anastomotic fibrosis is the main cause of re-operation. The present study aimed to investigate the therapeutic effect...

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Detalles Bibliográficos
Autores principales: Hou, Hong-Wei, Wang, Jin-Min, Wang, Dong, Wu, Rong, Ji, Zhen-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505014/
https://www.ncbi.nlm.nih.gov/pubmed/28627592
http://dx.doi.org/10.3892/ijmm.2017.3016