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A graph extension of the positional Burrows–Wheeler transform and its applications

We present a generalization of the positional Burrows–Wheeler transform, or PBWT, to genome graphs, which we call the gPBWT. A genome graph is a collapsed representation of a set of genomes described as a graph. In a genome graph, a haplotype corresponds to a restricted form of walk. The gPBWT is a...

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Detalles Bibliográficos
Autores principales: Novak, Adam M., Garrison, Erik, Paten, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505026/
https://www.ncbi.nlm.nih.gov/pubmed/28702075
http://dx.doi.org/10.1186/s13015-017-0109-9