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Vandetanib-eluting Radiopaque Beads: In vivo Pharmacokinetics, Safety and Toxicity Evaluation following Swine Liver Embolization

PURPOSE: To evaluate the plasma and tissue pharmacokinetics, safety and toxicity following intra-arterial hepatic artery administration of Vandetanib (VTB)-eluting Radiopaque Beads (VERB) in healthy swine. MATERIALS AND METHODS: In a first phase, healthy swine were treated with hepatic intra-arteria...

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Detalles Bibliográficos
Autores principales: Denys, Alban, Czuczman, Peter, Grey, David, Bascal, Zainab, Whomsley, Rhys, Kilpatrick, Hugh, Lewis, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505051/
https://www.ncbi.nlm.nih.gov/pubmed/28740542
http://dx.doi.org/10.7150/thno.19652