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E-selectin-targeted Sialic Acid-PEG-dexamethasone Micelles for Enhanced Anti-Inflammatory Efficacy for Acute Kidney Injury

The effective treatment for acute kidney injury (AKI) is currently limited, and care is primarily supportive. Sialic acid (SA) is main component of Sialyl Lewis(x) antigen on the mammalian cell surface, which participates in E-selectin binding. Therefore, dexamethasone(DXM)-loaded E-selectin-targeti...

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Detalles Bibliográficos
Autores principales: Hu, Jing-Bo, Kang, Xu-Qi, Liang, Jing, Wang, Xiao-Juan, Xu, Xiao-Ling, Yang, Ping, Ying, Xiao-Ying, Jiang, Sai-Ping, Du, Yong-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505054/
https://www.ncbi.nlm.nih.gov/pubmed/28740545
http://dx.doi.org/10.7150/thno.19571