Fli-1 overexpression in erythroleukemic cells promotes erythroid de-differentiation while Spi-1/PU.1 exerts the opposite effect

The ETS transcription factors play a critical role during hematopoiesis. In F-MuLV-induced erythroleukemia, Fli-1 insertional activation producing high expression of this transcription factor required to promote proliferation. How deregulated Fli-1 expression alters the balance between erythroid dif...

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Detalles Bibliográficos
Autores principales: Vecchiarelli-Federico, Laura M., Liu, Tangjingjun, Yao, Yao, Gao, Yuanyuan, Li, Yanmei, Li, You-Jun, Ben-David, Yaacov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505126/
https://www.ncbi.nlm.nih.gov/pubmed/28586009
http://dx.doi.org/10.3892/ijo.2017.4027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505126/
https://www.ncbi.nlm.nih.gov/pubmed/28586009
http://dx.doi.org/10.3892/ijo.2017.4027

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