Intermedin attenuates renal fibrosis by induction of heme oxygenase-1 in rats with unilateral ureteral obstruction

BACKGROUND: Intermedin [IMD, adrenomedullin-2 (ADM-2)] attenuates renal fibrosis by inhibition of oxidative stress. However, the precise mechanisms remain unknown. Heme oxygenase-1 (HO-1), an antioxidant agent, is associated with antifibrogenic effects. ADM is known to induce HO-1. Whether IMD has a...

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Detalles Bibliográficos
Autores principales: Qiao, Xi, Wang, Lihua, Wang, Yanhong, Su, Xiaole, Qiao, Yufeng, Fan, Yun, Peng, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505135/
https://www.ncbi.nlm.nih.gov/pubmed/28697727
http://dx.doi.org/10.1186/s12882-017-0659-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505135/
https://www.ncbi.nlm.nih.gov/pubmed/28697727
http://dx.doi.org/10.1186/s12882-017-0659-6

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