Cargando…

The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability

To achieve accurate spatiotemporal patterns of gene expression, RNA-binding proteins (RBPs) guide nuclear processing, intracellular trafficking, and local translation of target mRNAs. In neurons, RBPs direct transport of target mRNAs to sites of translation in remote axons and dendrites. However, it...

Descripción completa

Detalles Bibliográficos
Autores principales: Cosker, Katharina E, Fenstermacher, Sara J, Pazyra-Murphy, Maria F, Elliott, Hunter L, Segal, Rosalind A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505173/
https://www.ncbi.nlm.nih.gov/pubmed/27019013
http://dx.doi.org/10.1038/nn.4280