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Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA

Bacteria and archaea use the CRISPR–Cas system as an adaptive response against infection by foreign nucleic acids. Owing to its remarkable flexibility, this mechanism has been harnessed and adopted as a powerful tool for genome editing. The CRISPR–Cas system includes two classes that are subdivided...

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Detalles Bibliográficos
Autores principales: Alcón, Pablo, Montoya, Guillermo, Stella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505246/
https://www.ncbi.nlm.nih.gov/pubmed/28695850
http://dx.doi.org/10.1107/S2053230X1700838X