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Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA
Bacteria and archaea use the CRISPR–Cas system as an adaptive response against infection by foreign nucleic acids. Owing to its remarkable flexibility, this mechanism has been harnessed and adopted as a powerful tool for genome editing. The CRISPR–Cas system includes two classes that are subdivided...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505246/ https://www.ncbi.nlm.nih.gov/pubmed/28695850 http://dx.doi.org/10.1107/S2053230X1700838X |