CD8αα(+) Intraepithelial Lymphocytes Arise from Two Major Thymic Precursors

TCRαβ(+) CD8αα(+) intestinal intraepithelial lymphocytes (CD8αα IELs) are an abundant population of thymus-derived T cells that protect the gut barrier surface. We sought to better define the thymic IEL precursor (IELp) by analysis of their maturation, localization, and emigration. We defined two pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruscher, Roland, Kummer, Rebecca L., Lee, You Jeong, Jameson, Stephen C., Hogquist, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505317/
https://www.ncbi.nlm.nih.gov/pubmed/28530714
http://dx.doi.org/10.1038/ni.3751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505317/
https://www.ncbi.nlm.nih.gov/pubmed/28530714
http://dx.doi.org/10.1038/ni.3751

Ejemplares similares