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CD8αα(+) Intraepithelial Lymphocytes Arise from Two Major Thymic Precursors

TCRαβ(+) CD8αα(+) intestinal intraepithelial lymphocytes (CD8αα IELs) are an abundant population of thymus-derived T cells that protect the gut barrier surface. We sought to better define the thymic IEL precursor (IELp) by analysis of their maturation, localization, and emigration. We defined two pr...

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Detalles Bibliográficos
Autores principales:	Ruscher, Roland, Kummer, Rebecca L., Lee, You Jeong, Jameson, Stephen C., Hogquist, Kristin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505317/ https://www.ncbi.nlm.nih.gov/pubmed/28530714 http://dx.doi.org/10.1038/ni.3751

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