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Antinociceptive tolerance to NSAIDs in the agranular insular cortex is mediated by opioid mechanism

Several lines of investigations have shown that in some brain areas, in particular, in the midbrain periaqueductal gray matter, rostral ventromedial medulla, central nucleus of amygdala, nucleus raphe magnus, and dorsal hippocampus, microinjections of nonsteroidal anti-inflammatory drugs (NSAIDs) in...

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Detalles Bibliográficos
Autores principales: Pirkulashvili, Natia, Tsiklauri, Nana, Nebieridze, Marina, Tsagareli, Merab G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505549/
https://www.ncbi.nlm.nih.gov/pubmed/28740423
http://dx.doi.org/10.2147/JPR.S138360