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Efficacy of piroxicam for postoperative pain after lower third molar surgery associated with CYP2C8*3 and CYP2C9

OBJECTIVE: Nonsteroidal anti-inflammatory drugs (NSAIDs) are metabolized by the cytochrome P450 enzymes (CYPs), predominantly CYP2C8 and CYP2C9. The aim of this study was to evaluate the possible association of polymorphisms in the CYP2C8*3 and CYP2C9 genes with the clinical efficacy of oral piroxic...

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Detalles Bibliográficos
Autores principales: Calvo, Adriana Maria, Zupelari-Gonçalves, Paulo, Dionísio, Thiago José, Brozoski, Daniel Thomas, Faria, Flávio Augusto, Santos, Carlos Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505550/
https://www.ncbi.nlm.nih.gov/pubmed/28740425
http://dx.doi.org/10.2147/JPR.S138147