Mitosis can drive cell cannibalism through entosis

Entosis is a form of epithelial cell cannibalism that is prevalent in human cancer, typically triggered by loss of matrix adhesion. Here, we report an alternative mechanism for entosis in human epithelial cells, driven by mitosis. Mitotic entosis is regulated by Cdc42, which controls mitotic morphol...

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Detalles Bibliográficos
Autores principales: Durgan, Joanne, Tseng, Yun-Yu, Hamann, Jens C, Domart, Marie-Charlotte, Collinson, Lucy, Hall, Alan, Overholtzer, Michael, Florey, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505699/
https://www.ncbi.nlm.nih.gov/pubmed/28693721
http://dx.doi.org/10.7554/eLife.27134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505699/
https://www.ncbi.nlm.nih.gov/pubmed/28693721
http://dx.doi.org/10.7554/eLife.27134

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