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Mitosis can drive cell cannibalism through entosis
Entosis is a form of epithelial cell cannibalism that is prevalent in human cancer, typically triggered by loss of matrix adhesion. Here, we report an alternative mechanism for entosis in human epithelial cells, driven by mitosis. Mitotic entosis is regulated by Cdc42, which controls mitotic morphol...
Autores principales: | Durgan, Joanne, Tseng, Yun-Yu, Hamann, Jens C, Domart, Marie-Charlotte, Collinson, Lucy, Hall, Alan, Overholtzer, Michael, Florey, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505699/ https://www.ncbi.nlm.nih.gov/pubmed/28693721 http://dx.doi.org/10.7554/eLife.27134 |
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