Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4(+) T cells

Although antiretroviral therapy can suppress HIV-1 infection to undetectable levels of plasma viremia, integrated latent HIV-1 genomes that encode replication competent virus persist in resting CD4(+) T cells. This latent HIV-1 reservoir represents a major barrier to a cure. Currently, there are sub...

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Detalles Bibliográficos
Autores principales: Gupta, Phalguni, Sanyal, Anwesha, Ratner, Deena, Ding, Ming, Zerbato, Jennifer M., Giacobbi, Nicholas, Venkatachari, Narasimhan J., Patterson, Bruce K., Chargin, Amanda, Chen, Yue, Mailliard, Robbie B., Rinaldo, Charles R., Sluis-Cremer, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505781/
https://www.ncbi.nlm.nih.gov/pubmed/28553933
http://dx.doi.org/10.1038/nm.4347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505781/
https://www.ncbi.nlm.nih.gov/pubmed/28553933
http://dx.doi.org/10.1038/nm.4347

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