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Enhanced Depolymerization of Actin Filaments by ADF/Cofilin and Monomer Funneling by Capping Protein Cooperate to Accelerate Barbed-End Growth

A living cell’s ability to assemble actin filaments in intracellular motile processes is directly dependent on the availability of polymerizable actin monomers, which feed polarized filament growth [1, 2]. Continued generation of the monomer pool by filament disassembly is therefore crucial. Disasse...

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Detalles Bibliográficos
Autores principales: Shekhar, Shashank, Carlier, Marie-France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505869/
https://www.ncbi.nlm.nih.gov/pubmed/28625780
http://dx.doi.org/10.1016/j.cub.2017.05.036