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Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats

Typically, bone regenerative medicine is applied to repair bone defects in patients with osteoporosis. Meanwhile, there is an urgent need to develop safe and cheap drugs that induce bone formation. Icariin, which is reported to promote the osteogenesis of stem cells in vitro, is the main active comp...

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Detalles Bibliográficos
Autores principales: Wu, Yuqiong, Cao, LingYan, Xia, Lunguo, Wu, Qianju, Wang, Jie, Wang, Xiao, Xu, Lianyi, Zhou, Yuning, Xu, Yuanjin, Jiang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505963/
https://www.ncbi.nlm.nih.gov/pubmed/28698566
http://dx.doi.org/10.1038/s41598-017-05392-z