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Flavonoid Enhances the Glyoxalase Pathway in Cerebellar Neurons to Retain Cellular Functions

Oxidative stress is damaging to cells and contributes to aging and neurodegenerative disease. This state is mediated by production of imbalanced molecules, and reactive dicarbonyl compounds - mainly methylglyoxal. The glyoxalase pathway is an antioxidant defense system utilized to detoxify methylgly...

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Detalles Bibliográficos
Autores principales: Frandsen, Joel, Narayanasamy, Prabagaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505997/
https://www.ncbi.nlm.nih.gov/pubmed/28698611
http://dx.doi.org/10.1038/s41598-017-05287-z